Feline PRC or Panleukopenia Rhinotracheitis Calicivirus: Panleukopenia (PRC) or feline distemper is the most contagious of all cat diseases. Common symptoms are fever, loss of appetite, vomiting, and diarrhea. Transmission occurs most commonly by direct contact with infected cats or their excretions. During the early stages of the infection, virus is shed in feces, urine, saliva, and vomit. In addition, fleas may transmit FPV from infected to susceptible cats during the acute stage of the disease. The virus may also be spread by contact with contaminated objects, such as food bowls, litter pans, bedding, cages, or by peoplepersons (on hands or clothing, for example).

Rhinotracheitis (PRC) is a very contagious respiratory disease that causes sneezing, loss of appetite, fever, and eye inflammation. As the virus progresses, a discharge is noticeable from both the eyes and the nose. Rhinotracheitis is transmitted through the air and direct contact. The virus is shed in saliva, eye, and nasal secretions.     Calicivirus (PRC) is another serious feline respiratory infection. It is often present along with rhinotracheitis and signs of this infection are similar to Rhinotracheitis. Cats with Calicivirus may also develop tongue ulcers. Calicivirus is spread through direct contact with the saliva, eye and nose discharges, and sometimes the feces of an infected cat.

This is a combination vaccine called PRC and is started at 6 weeks of age with a second dose 3 weeks later and a third dose at 12 weeks of age, then repeated once annually.