Canine Distemper: This is a widespread, often fatal disease that can result in severe multi-systemic disease involving the respiratory and gastrointestinal tract, as well as the skin and central nervous system. Infected dogs spread the virus through bodily secretions and excretions, especially respiratory secretions. It is mainly transmitted in airborne viral particles that dogs breathe. Dogs in recovery may continue to spread the virus for several weeks after symptoms disappear. However, once they are fully recovered, they no longer spread the virus. Early symptoms include fever, loss of appetite, and mild eye inflammation that may only last a day or two. Symptoms become more serious and noticeable as the disease progresses. Dogs may also experience eye and nose discharge, depression, and loss of appetite. Most dogs that die from distemper die from neurological complications.